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A New Study Reveals Why You Should Never Drink ‘Zero Calorie’ Or ‘Sugar Free’ Drinks: Leads To Weight Gain And Cardiovascular Risk

April 25, 2025 by Mariam Qayum

 
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“Zero calorie” or “sugar-free” drinks might sound like a guilt-free way to enjoy your favorite beverages while trying to lose weight—but they might not be as harmless as they seem. Many of these drinks are sweetened with artificial ingredients like sucralose, which can actually have the opposite effect of what you’re aiming for. Despite having no calories, sucralose has been linked to increased cravings, changes in gut health, and even disrupted metabolism—all of which can potentially contribute to weight gain over time.

Sucralose linked to weight gain

Recent research is raising serious concerns about sucralose, the artificial sweetener commonly found in “zero calorie” and “sugar-free” drinks. A large-scale review published in the Canadian Medical Association Journal, which analyzed data from over 400,000 participants, found that sucralose consumption was associated with higher body mass index (BMI) and an increased risk of heart-related issues.

These findings support earlier studies suggesting that artificial sweeteners like sucralose may actually encourage fat storage in the body rather than help with weight loss, as often advertised. Despite being marketed as “diet-friendly,” growing scientific evidence shows that these sweeteners can interfere with metabolism and overall health.

Even more alarming, animal research has linked sucralose to leukemia and other blood cancers, while a 2023 study from North Carolina found that a chemical formed during the digestion of sucralose can damage DNA and contribute to leaky gut—two factors that may raise the risk of chronic illness, including cancer.

Healthier alternative

If you're looking to cut back on sugar without relying on artificial sweeteners like sucralose, there are healthier, more natural alternatives to consider. Options like stevia, monk fruit extract, and erythritol are plant-derived and tend to have less impact on blood sugar levels. For an even more wholesome approach, try naturally sweetening drinks and recipes with a splash of fruit juice, mashed berries, or a dash of cinnamon or vanilla. These alternatives not only provide a touch of sweetness but also come with antioxidants, fiber, and other nutrients that support overall health—without the potential risks linked to artificial sweeteners.

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