1. Remove Irritants
As part of the 4R protocol, you want to remove irritants. The remove step involves eliminating harmful elements such as pathogens or food allergens that may contribute to gut issues.
Lee says, "Irritants such as pathogens and other inflammatory triggers that aren't supporting a healthy gut [should be removed.] Reduce or avoid stress, alcohol, high sugar foods, refined carbohydrates, food sensitivities, and trans/saturated fats. Chronic inflammation in the body can impair gut health and promote weight gain."
2. Replace Inflammatory Foods
The replace phase focuses on replenishing digestive enzymes and essential substances that may be lacking. As Lee states, "Replace inflammatory foods with anti-inflammatory and supportive foods for the gut. Include 30 different and colorful plant foods each week, because it provides a variety of fiber and polyphenols that are anti-inflammatory and support a healthy gut.
She also names other anti-inflammatory foods we can add to our diet to further maximize the 'replace' protocol. "Other anti-inflammatory foods to include are: omega-3 fatty acids from salmon or sardines, herbs and spices like turmeric or rosemary, and extra virgin olive oil. This is also the step where we might consider additional digestive support, through enzymes or gallbladder and liver support. Reducing inflammation can support healthy weight loss and gut health."
3. Reinoculate
The reinoculate step involves introducing beneficial bacteria, often through probiotics, to restore a healthy balance in the gut microbiome. This step recognizes the importance of a balanced and diverse community of bacteria for optimal digestive health.
"Reinoculate your gut microbiome with beneficial bacteria or probiotics. Incorporate more probiotic or fermented foods like yogurt, kefir, sauerkraut or kimchi, because they contain live beneficial microorganisms that can diversify your gut microbiome. Probiotics provide more anti-inflammatory effects, which can support weight loss. There is also evidence to show a balanced gut helps with weight management," Lee notes.
4. Repair
During the repair phase, individuals often incorporate nutrients that support tissue healing, such as amino acids, vitamins, and minerals. These components play a crucial role in rebuilding and strengthening the mucosal lining of the gastrointestinal tract, which may have been compromised by factors like inflammation, stress, or an imbalanced diet.
"A poor gut lining can allow undigested food, pathogens, and unwanted bacteria to leak back into our system leading to inflammation and possibly weight gain. This step is important to maintaining overall gut health and healthy gut microbiome. You can support your gut lining with foods high in collagen, L-glutamine, zinc and vitamin C," Lee highlights.