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Food

The One Type Of Food That Is Linked To 'Major Age-Related Diseases' And Can 'Accelerate Aging': 'Contributes To Cell Damage'

February 21, 2025 by Mariam Qayum
shefinds | Food
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Aging is a natural process, but certain lifestyle choices can accelerate age-related diseases such as diabetes, heart disease, and cognitive decline. One major contributor is a diet high in processed sugars, which can lead to chronic inflammation, insulin resistance, and oxidative stress—all of which speed up aging and increase the risk of diseases.

To learn more about the link between processed foods, age-related diseases, and discover some of the worst options you should consider cutting out of your diet, we spoke to Robert Iafelice, MS, RDN, Nutrition Expert at SETFORSET and Nancy Mitchell, registered nurse. They told us that foods high in processed sugarsdonuts in particular—should be avoided as much as possible. Find all of their insights below!

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Foods high in processed sugars linked to age-related diseases

The reason many foods high in processed sugar contribute to premature aging and age-related diseases is because they promote inflammation, insulin resistance, and oxidative stress, which accelerate aging at the cellular level. Processed sugars add to glycation, a process where sugar molecules attach to collagen and elastin, making skin more prone to wrinkles, sagging, and dullness. These sugars have been associated with diabetes, heart disease, and even cognitive decline.

“A diet high in processed sugars may increase your risk of developing Alzheimer’s disease,” Mithcell warns. In fact, she points out that Alzheimer’s disease is frequently referred to as “diabetes of the brain” due to its link to high blood glucose levels and insulin resistance. “Studies suggest that chronically high blood glucose may contribute to cell damage throughout the nervous system, including the parts of the brain associated with this neurodegenerative disease,” she warns. Yikes!

Iafelice agrees, explaining that sugar is toxic to your body’s cells, and eating too much of it by consuming foods like donuts will lead to insulin resistance over time. “Chronic consumption of sugar can lead to elevated blood sugar over time, which is essentially diabetes. As we get older, our cells become more resistant to insulin, which lowers blood sugar,” he says, noting that insulin resistance leads to high blood glucose levels. As it turns out, research shows that brain cells can also become resistant to insulin, “and thus cannot use glucose to efficiently fuel the brain.” According to Iafelice, “This may be a key factor in the epidemic of Alzheimer's,” because “without energy, brain cells die off.”

“High sugar from the diet can lead to chronically high blood sugar. This is very favorable for the growth of cancer cells.”

Additionally, high blood sugar can raise your risk of heart disease. “High blood sugar is inflammatory, and inflammation promotes plaque formation and cardiovascular diseases,” he says. “There you have it… all the major age-related diseases linked to high blood sugar.”

To make matters worse, there’s also the issue of the unhealthy fats that donuts and many other sweet treats can pack in. “Bad fats (e.g., trans fatty acids and too many omega-6 fats) get into the membranes and make them more rigid and less responsive to insulin. This fosters insulin resistance. So, pair too much sugar with unhealthy fats, and you get accelerated aging,” Iafelice adds.

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The bottom line

Iafelice suggests eating dark chocolate that’s at least 85% cocoa solids or dark chocolate-covered nuts. So, “basically something without a lot of sugar and/or unhealthy fats” will be a better choice. And while you may miss the sugary goodness of a donut, taking care of your body will be well worth it in the long run.

Author:

Editorial Assistant

Mariam is an Editorial Assistant and writer at SheFinds, covering everything from style and beauty to health and wellness. Splitting her time between New York and Philadelphia, she brings a sharp eye for trends and a passion for storytelling to the digital space. With a strong editorial background, she’s always exploring the latest in fashion, skincare, and wellness. When she’s not writing or pitching, you’ll find her in the kitchen experimenting with new recipes or planning her next travel adventure. You can reach Mariam at mariam@shefinds.com.

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Moringa powder and fresh leaves arranged on a wooden table.
Woman using fabric softener while doing laundry at home.
Fit woman enjoying avocado, cucumber, tomatoes, and walnuts.
Cottage cheese topped with fresh berries in a bowl.
Best yogurt options alongside the worst processed meats.
Stracciatella dipped cookie sandwiches with coolers from Aldi.
Pan-fried salmon served on a plate with kale garnish.
Black bean taco salad bowl loaded with fresh ingredients.
Woman snacking on chips in a casual setting.
Leafy greens, eggs, and steak alongside a woman with hair loss.
Checking blood sugar level with a glucose meter.
Gwyneth Paltrow at The Fashion Awards red carpet event.
Walmart storefront showcasing a variety of products.
Colorful food dyes displayed in small containers.
Person grabbing an avocado while shopping in a grocery store.
Woman stepping onto a scale for weight check.
Straw tote bag with Magic Spoon protein treats from Aldi.
Person drinking soda from a can in a casual setting.
Woman walking on a treadmill during workout session.
High-protein breakfast spread featuring eggs, avocado, and toast.